•
allele
英:【əˈli:l】美:【əˈlil】
英:
美:
n.
等位基因
形容词:
allelic
名词:
allelism
1 、Of the 21 patients conservatively treated between 1975 and 1997, 12 had diffuse disease (homozygous mutant
allele
s) and 9 had presumed focal disease (paternal mutant
allele
only).───1975年至1997年期间接受保守治疗的21例患者中,12例为弥漫**变(等位基因突变纯合子),9例为局灶**变(仅父系等位基因突变)。
2 、HLA-DRB1 ~*1301/1302
allele
may be a resistant gene which in patients with hepatitis B in Henan Han nationality to clear viral hepatitis B.───HLA-DRB11301/1302等位基因可能是河南乙型肝炎人群中清除HBV病毒的抗病基因。
3 、The results suggest that ICAM-1 K469E polymorphism is significantly associated with susceptibility of stroke,E
allele
and EE homozygote may be risk factors for ischemic stoke.───ICAM-1基因K469E多态性与缺血性脑卒中发生的易感性有关,E等位基因可能是脑卒中发生的遗传易感标记,纯合突变EE基因型可能是脑卒中的危险因素。
4 、In the control group, the frequency of
allele
0501 was the highest (24.24%).───*0501等位基因频率在对照组中高达24.24%,而在患者中仅为5%;
5 、However, they found three
allele
s in the fingernail scrapings.─── 然而 他们在指甲残留物里发现了三个等位基因
6 、SNP values belong to {0, 1, 2, ?}, where 0s and 1s denote homozygous sites with major
allele
and minor
allele
, respectively;2s stand for heterozygous sites, and ?───SNP的价值观属于{0 , 1 , 2 , ? ) , 其中0和1的字首合子具大等位基因与小等位基因,分别;
7 、It has been reported in foreign literature that the A 1
allele
of the Taq I polymorphism of the dopamine D 2 receptor gene(DRD 2)was related to ADHD.───国外近年由于分子生物学方法的介入,发现多巴胺D2受体TaqIA1等位基因与本病相关。
8 、Our results indicated that SAD was inversely associated with C/C genotype and C
allele
of NQO1 gene.───NQO1基因多态性与SAD发病明显关联 ,NQO1基因 6 0 9序列C/C基因型、C等位基因与SAD发病呈明显负关联。
9 、The distributions of three genotypes and two
allele
s between two chicken breeds were very similar and the frequencies of genotype CC and
allele
C were highest among them.───两个等位基因和三种基因型在两鸡种中的分布基本一致。其中,基因型CC和等位基因C的频率最高。
10 、The
allele
frequencies of the ALAD1 and ALAD2 were 0.967 and 0.033, respectively.───ALAD1和ALAD2等位基因频率分别为0.967和0.033。
11 、No significant differences of genotype and
allele
frequencies between the matched groups were found.───各相匹配组间比较未发现基因型和等位基因频率的显著性差异。
12 、A deletion of adenosine (A), at -241 (relative to initiation codon ATG), designated as Del(A)
allele
, was found in Laiwu compared with Yorkshire (GenBank accession number DQ463321-22).───克隆了猪DGAT1 5’调控区的部分序列(737 bp),在-241bp(相对于起始密码子ATG)发现一处由单个腺嘌呤(A)缺失产生的新SNP位点(定义为等位基因Del(A) ) (GenBank收录号:DQ463321-22);
13 、The
allele
frequencies in the three populations are consistent with that of the Mongoloid.───他们的基因频率与蒙古人种其他人群是一致的。
14 、Only the patients carrying the
allele
M235T have correlation between genotype DD of ACE and preeclampsia.───ACE基因DD型与子痫前期的相关性限于携带有M235T等位基因的患者。
15 、"People who carry the E4
allele
may not be able to recoer as effectiely from a brain injury, making these newborns at greater risk for deeloping cerebral palsy," he said.───他说:“具有E4等位基因的人可能很难从脑部损伤充分恢复健康,并可能会使新生儿具有发展脑瘫的更大风险。”
16 、There was significant difference between A
allele
and G
allele
of GSTP_(1-105) groups(P───GSTP1-105变异基因型频率差异非常显蓍(P
17 、Genetic drift is responsible for losing an existing
allele
due to random sampling.─── 由于随机取样 遗传漂变会导致失去现有的一个等位基因
18 、Among the known aldh2
allele
s, the aldh2*2
allele
is rare in most populations, but common in Asian and Mongolian races.───在亚洲的黄种人群中,aldh2*2是频率最高且最重要的突变型。
19 、We found 9 ACn (n=16-24)
allele
s,among them,the
allele
AC21 was the commonest one.───共发现9种等位基因,ACn重复数目为16至24。
20 、The
allele
C in AIH group (90. 9%) of C-988A was lower than healthy group,but
allele
A(9. 1%) was higher(P───AIH组C-988A多态性C(90.9%)下降而A(9.1%)上升,CC降低,CA、AA上升(P
21 、An emphasis on purity in contrast is exclusionary and selective, and in the long run is counterproductive to insuring the survival of the magic
allele
.───与此对立的对于纯血统的强调是排他并且有选择的,长远地说是与保证魔法基因等位体的生存格格不入的。
22 、The frequencies of the
allele
E and e of the Ningxiang, Daweizi and Duroc were almost equal.───只有杜洛克猪的等位基因E的频率略小于等位基因e的频率,在其余四品种中,都是等位基因E的频率大于等位基因e的频率。
23 、An
allele
does not care if it is in a half-blooded (heterozygous) or pure-blooded (homozygous) individual.───一个基因等位体无论存在于混血(杂生)或纯血统(同生)的人中对其本身并不造成任何差别。
24 、Indeed, the only way we could assert that there was a gene in an organism was by finding a mutant
allele
for it.───事实上,唯一能确定一个生物体内存在某一种基因的方法就是找到这个基因的突变等位基因。
25 、The DR1501
allele
is associated with a more benign course, whereas the DR1502 is associated with severe forms of the disease.───DR1501等位基因与良性过程相关,而DR1502与疾病的严重形式相关。
26 、P is the frequency of the most common
allele
.───代表最常见等位基因的频率。
27 、However,the DD genotype and D
allele
had higher frequency in NIDDM with retinopathy than without.───DD 型与D 等位基因在DR( + ) 组出现频率高,DR( + ) 组与DR( - ) 组相比,基因型及等位基因分布差异具显著性。
28 、Frequency of AA genotype is the highest,and that of A
allele
is obviously higher than that of B
allele
in two yak breeds.───在两种牦牛品系中,AA基因型频率最高,A等位基因频率均明显高于B等位基因频率.
29 、B1,B2
allele
frequencies of CETP gene were 54.25%, 45.75%,and similar to that of Caucasian, and yellow race.───CETP-TaqIB基因B1、B2等位基因频率为54.25%和45.75%,与欧美白种人、黄种人均相近。
30 、For BM2113,
allele
C (142bp) had a positive correlation with gam girth, net meat weight and net meat rate.───BM2113等位基因C(142bp)对腿围、净肉重和净肉率等性状有正向影响;
31 、Alternatively 【in deletions】, we should consider the other nondeleted
allele
and perhaps discover that specific variants on that chromosome are predisposing to these diseases.───另一方面(在基因去除方面),我们应该考虑其他未被去除的对偶基因,或许发现染色体上倾向造成该疾病的染色体特定变异。
32 、ACE gene is associated with Kidney asthenia type of DN,and the
allele
of D and the genetype of DD maybe the genetic base of the kidney asthenia.───ACE基因不同基因型与DN肾虚关系密切 ,ACE基因之D等位基因及DD型可能是DN肾虚的基因基础
33 、The value of the
allele
may have been changed, may have been blurred, it doesnt matter.─── 等位基因的数值可能被改了 也可能被模糊了 这都没关系
34 、An
allele
can not be "watered down" by outcrossing.───一个基因等位体不会由于与异体通婚而被稀释。
35 、The thinner entorhinal cortex in individuals with the 4
allele
might contribute to risk of Alzheimers disease.───具有等位基因4的个体,其较薄的内嗅皮层会增加阿耳茨海默(氏)病的风险。
36 、G2963A in the coding-region of TBX1gene was associated with CTD and people with G
allele
have much higher risk in the pathogenesis of CTD.───TBX1基因编码区的SNP位点G2963A与人类圆锥动脉干畸形有明显的相关性,具有G等位基因的人发生圆锥动脉干畸形的危险性相对增高。
37 、The frequency of
allele
Z-2 was significently higher in DRP group than in NDC group and CON group, but the the frequency of
allele
Z+2 was much lower.───Z+ 2等位基因频率在DRP低于NDC和CON组。
38 、The frequencies of frequencies of the ACE D
allele
in EHT groups of were hig her than that in the health controls, respectively (P───EHT组ACE I/ D基因多态性等位基因频率 I为 0 .50 ,D为 0 .50 ,D等位基因频率及基因型频率显著高于 NT组 ( P
39 、In small populations, fixation to a single surviving
allele
can occur in just a few generations.───在小的群体中,对继续存在的等位基因的固定,可能在短短的几代里发生。
40 、The subjects carrying
allele
of MPO rs7208693 A and UGT1A6 rs6759892 G or rs1105879 C at the same time could be more susceptible to BP.───同时携带MPO基因rs7208693A和UGT1A6基因rs6759892G或rs1105879C等位基因型个体对苯中毒易感;
41 、They then analyzed the DNA of the sterile males and identified the
allele
that caused the infertility.───他们分析了不育雄性小鼠的DNA,鉴定出导致不育的等位基因。
42 、In the coronary angiography follow-up cases, the frequency of KK genotype and E
allele
carriers in the patients with restenosis were 58.3%, 41.7% respectively.───再狭窄患者中KK纯合子和E等位基因携带基因型的频率分别为 5 8 3%、4 1 7% ;
43 、The HBA was the preponderant
allele
,and the HBAA was the preponderant genotype. Their frequencies were 0.799 and 0.610 4 respectively.───其中HBAA和HBA分别为优势基因型和优势等位基因,其频率分别为0.6104和0.799。
44 、In Yi nationality of Yunnan, HLA-DQA10301
allele
may be a susceptible gene and the HLA-DQA10601
allele
may protect individuals from the risk of diabetes mellitus.───HLA-DQA10301是云南彝族2型糖尿病的易感基因; HLA-DQA10601是云南彝族2型糖尿病的保护基因。
45 、The B
allele
frequency of ESR gene in Erhualian sows is high and has a close relativity to TNB and NBA.───二花脸猪ESR座位B基因基因频率较高,并且和高产仔数和产活仔数高度相关;
46 、Frequency of AA genotype was the highest, abd frequency of A
allele
was obviously higher than frequency of B
allele
in four sheep breeds.───在4个绵羊品种中,AA基因型频率最高,A等位基因频率明显高于B等位基因频率。
47 、Tracers going to 12 strands on three different
allele
s.─── 追踪器在三个不同的等位基因上分成12股
48 、The phenotypes of both
allele
s are expressed.─── 兩個等位基因的表型應該這樣表示
49 、In the F_2 chickens of 15 full-sib families, the frequency of the
allele
A and B are 92.5% and 7.5% respectively.───在15个全同胞家系F_2代群体中,用PCR-SSCP方法检测该突变位点不同基因频率分布,结果表明等位基因A为29.15%,等位基因B为70.85%。
50 、Those RNAs are produced only from the
allele
on the maternal chromosome.───同时,只有来自母系染色体上的对偶基因才会制造这些RNA。
51 、In drift each
allele
in a population is randomly and independently affected, yet the fluctuations in their
allele
frequencies are all driven in a quantitatively similar manner.───在漂变时,一个群体中的每个等位基因受到的影响是随机的和独立的,但它们的等位基因频率波动都是由数量上相似的方式推动。
52 、Whereas the prevalence of Arg
allele
was 87.0% and XRCC1 399
allele
Gln was 13.0%.───XRCC1399(Arg/Arg、Arg/Gln、Gln/Gln)三种基因型频率分别为49.3%、45.3%和5.3%。
53 、Mutations in three genes (APP, PSEN1, and PSEN2) have been found to cause AD and APOE4
allele
increases the risk of the disease.───发生在三个基因(APP, PSEN1, PSEN2)中的突变可导致该病,而APOE4等位基因与患病的危险增加有关。
54 、The frequency of the L-selectin gene 21**
allele
in CHD patients was significantly higher than that in the control group (77.59% vs 69.35%, P=0.006).───冠心病组21**等位基因频率明显高于对照组(77.59%vs69.35%,P=0.006)。
55 、According to the population genetic structure the RYR gene of n -
allele
frequencies were higher in Duroc and Yorkshire ,but was completely absent in Landrace.───从群体遗传结构分析表明:在约克夏,杜洛克猪群中,有n基因存在;
56 、EF=0.82>0.The gene frequency of HLA-DRB*040x
allele
in illness groupe(3%) was lower than the control(11.9%).───EF=0.82>0; 病例组HLA-DRB1*040x基因频率为3%,比对照组11.9%降低。
57 、Again, one dominant
allele
B is necessary in any dog to get the normal black pigment.───同样,有B位基因的显性基因狗就会显示正常的黑色。
58 、Compared with BsmI polymorphism,the distribution of ApaI polymorphism of the VDR gene is balanced, and thefrequency of A
allele
is 67.7%.───ApaI 多态性分布相对较均衡, A 等位基因频率为 67.7%,是优势基因。
59 、No significant differences were found in the frequencies of
allele
and genotype of the two SNPs (SNP1 and SNP2) of PTGS2 gene and one SNP(SNP3) of PLA2G4A gene between the case and the control(P>0.05).───PTGS2基因的两个 SNPs(SNP1和 SNP2 )与 PL A2 G4 A基因的一个 SNP(SNP3)的等位基因和基因型在病例组和对照组的频数分布差异无显著性 (P>0 .0 5 )。
60 、There were no significant differences in genotype frequencies and
allele
frequencies of MCP-1 gene between type 2 diabetes mellitus group and normal control group(P>0.05).───2型糖尿病组与正常对照组的MCP-1等位基因和基因型频率比较差异无统计学意义(P>0.05);
61 、When an organism is heterozygous for a trait, the resulting phenotype for that trait expresses only the dominant
allele
.───因此,生物的表型与基因型是不同的。
62 、The FDA has recently approved a genetic test (Invader UGT1A1, made by Third Wave Technologies, Inc.) to aid in the detection and identification of mutations in the UGT1A1*28
allele
.───2005年8月FDA批准了一个由第三波科技公司(好眼熟的名字)生活的基因检测试剂盒用于检测UGT1A1*28基因型。
63 、Key words: Par allel mechanism; BLDC;Motion control; Position analysis.───关键词:并联机构;无刷电机;运动控制;位置分析
64 、Frequency of varieties with Pina-DIa /Pinb-DIa and Pina-DIa /Pinb-DIe
allele
s ,which was relatively higher than the other Pin-DI
allele
wheat,was 25.4% and 10.3%, respectively.───不同类型间硬度存在差异,其中Pina-DIb/Pinb-DIa和Pina-DIa/Pinb-DIb品种的硬度值高于Pina-DIa/Pinb-DId、 Pina-DIa/Pinb-DIe 和Pina-DIa/Pinb-DIf基因的品种,差异达到0.05显著水平;
65 、AGT mutant 235T gene is associated with the pathogenesis of preeclampsia and its T
allele
may be a susceptible factor for preeclampsia.───AGT变异基因235T与子痫前期发生有关,T等位基因可能是子痫前期的易感基因。
66 、A
allele
of AGT might be a genetic contributor for patients with HCM to develop left ventricular outflow obstruction.───AGT的A等位基因可能是HCM病人发生左心室流出道梗阻的危险因子。
67 、Remember that in codominance, neither
allele
is recessive.─── 記住 共顯性表示 兩個等位基因都不是隱性的
68 、In control group the frequencies of (+/-) genotype and (+)
allele
were 10.7% and 5.3%, lower than Caucasian and Japanese population.───其中对照组 (+ - )基因型和 (+)等位基因的频率分别为 10 7%和 5 3% ,低于报道的白种人及日本人变异频率 ;
69 、The frequency of D
allele
genotype in ISR group (51.7%) was far higher than that of non-ISR group (28.8%).───卡方检验结果显示再狭窄组D等位基因频率(51.7%)明显高于未狭窄组D等位基因频率(28.8%)。
70 、For ETH225,
allele
A (123bp) had a positive correlation with waist corner width.───ETH225等位基因A(123bp)对腰角宽具有正向影响;
71 、In children the frequency of heterozygote was 35.7% and
allele
(+) was 17.9%,that similar to internal reports(14.7%),but much less than caucasian(43%).───30 8名儿童杂和突变型检出率为 35 7% ,等位基因 (+)频率为 17 9% ,与国内其它报道相近 (14 7% ) ,但远低于白种人群频率 4 3% ;
72 、A relationship among
allele
s where both
allele
s contribute to the phenotype of the heterozygote.─── 是指等位基因間的關系 兩個等位基因構成雜合子的表型
73 、The CYP2D6
allele
frequencies were aligned to *10, *1, *2, *5 from the highest to the lowest, with CYP2D6*10*10 as the most frequent genotype frequency (47.4%).───CYP2D6等位基因频率由高到低依次为~*10、~*1、~*2、~*5,CYP2D6~*10~*10基因型频率最高,占47.4%;
74 、The surprisingly high prevalence of random
allele
inactivation in human cells can generate diversity in gene expression that affects cell fate and physiology.───人类细胞等位基因随机失活可以产生多样性的基因表达,影响细胞命运和生理学的高普遍性令人惊讶。
75 、A condition in which the action of one gene conceals or suppresses the action of another gene that is not its
allele
but that affects the same part or biochemical process in an organism.───下位一个基因隐蔽或压迫另一个不是它的等位基因的基因的活动,但是后一个在有机体中影响同样的部位或生化进程
76 、In the 193 subjects,120(66.2%)were identified as VDR bb genotype,64(33.2%)as Bb,and 9(4.6%)as BB.The b
allele
frequencies reached 78.76%,and B
allele
frequencies was 21.24%.───193例测试对象中,维生素D受体基因型分别为bb型120例(62.2%)、Bb型64例(33.2%),BB型9例(4.6%); b等位基因频率为78.76%,B等位基因频率为21.24%。
77 、DD genotype and D
allele
is closely related to IR and abnormal plasm lipid metabolism,but I
allele
is not.───ACE基因DD型和D等位基因与IR及血脂代谢异常有关 ,与I等位基因则无关
78 、The silent
allele
of an imprinted gene is almost always highly methylated, for example.───例如,受铭印基因当中,遭到消音的对偶基因上头,绝大多数都具有高度的甲基化。
79 、For BMS1248,
allele
128 had positive effect on circumference of cannon bone.───BMS1248基因座的等位基因128对管围有正效应。
80 、Analyzing distribution of ACE gene I/D
allele
and genotypes in a OSA family.───(2 )观察 ACE I/ D多态在一个 OSA典型家系中的分布。
81 、To prevent the error causing by uncertain
allele
frequencies, a conservative CPI value should be calculated in paternity testing.───为了防止等位基因频率不确定性带来的误差,建议在亲权鉴定中用保守法计算CPI值。
82 、So Bieber suggested the type of kinship analysis and weighted
allele
probabilities used to connect family members with loved ones lost in the World Trade Center attacks.───因此,毕伯建议可以用这种血亲分析法,并考虑对位基因机率,用来协助家庭找寻在纽约世贸中心丧生的亲人。
83 、the
allele
s that match the male in this sample.─── 这个样本里能和这位男性配对的基因对
84 、The frequencies of the DD genetype and the D
allele
in Kidney Yang asthenia were significantly higher than in Kidney Yin asthenia (P───且肾阳虚证DD型频率与D等位基因携带率明显高于肾阳虚证 (P
85 、The number of
allele
X+ of ApoB in patients with CAD was obviously more than that in control group (P───冠心病组X+等位基因频率与正常对照组比较有统计学意义(P
86 、The results showed T
allele
had positive effect in locomotion, excitability and exploration.───初步认为该位点可作为衔取欲和游戏欲的辅助选择标记。
87 、The pro-diabetic variations that were found tended to increase the risk of the disease by between 10% and 25% per
allele
.───发生糖尿病之前的变异寻找每一个等位基因会提高10%-25%的患病风险。
88 、For ETH225,
allele
A(123bp)had a positive correlation with waisr corner width.───ETH225等位基因A(123bp)对腰角宽具有正面影响;
什么是等位基因?并举例.谢谢?
等位基因(allele),是指位于一对同源染色体相同位置上控制同一性状不同形态的基因
生物的形态、结构、生理特征称为性状。比如人的眼睑形态就是一种性状,这种性状有不同的表现形式:双重睑(俗称双眼皮)、单重睑(superiorepiblepharon上睑赘皮,俗称单眼皮),其中单重睑为隐性,双重睑为显性。我们把它们称为相对性状(其概念是同种生物同一性状的不同表现类型)。性状又是由基因控制的,控制显性性状的为显性基因(用大写字母,如A),控制隐性性状的为隐性基因(用小写字母,如a)。基因在体细胞中成对存在,所以一个个体的基因型就有:AA,Aa,aa,不过也有发生了染色体变异导致有多个基因。A和a就可以表示一对等位基因
什么是等位基因?并举例.谢谢?
等位基因是指同源染色体上控制相对性状的一对基因。注意一下相对性状的概念,它是指某种性状的不同表现形式,如同样是颜色,可表现为黑和白两种形式,那么黑和白就是一对相对性状。A与a分别控制显性和隐性性状,所以它们是等位基因,而A与A、a与a控制的都是相同的性状,所以它们不能称为等位基因,只能称相同基因。